PANGENOME MAP
Why in News?:
Recently, a new study has been published in the Nature journal describing a Pangenome Reference Map, built using genomes from 47 anonymous individuals (19 men and 28 women), mainly from Africa but also from the Caribbean, Americas, East Asia, and Europe.
What is a Pangenome Map?:
The pangenome, unlike the previous linear reference genome, is represented as a graph. Each chromosome in the pangenome can be imagined as a bamboo stem with nodes.
These nodes represent stretches of sequences that are similar among all 47 individuals. The internodes between the nodes vary in length and represent genetic variations among individuals from different ancestries.
.jpg)
.jpg)
